생명공학대학 - 융합생명공학과

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관심분야

Molecular plant-geminivirus interactions 
Translational research : Side effect alleviation of cancer patients 
Antiviral protein development : Nucleic acid hydrolytic catalytic antibody

학력

  • (Ph.D.) 미국 Ohio Sate University

약력/경력

  • 1995년 ~ 현재: 성균관대 유전공학과 조교수, 부교수, 교수

학술지 논문

  • (2023)  REPercussions: how geminiviruses recruit host factors for replication.  FRONTIERS IN MICROBIOLOGY.  14, 
  • (2023)  Coat protein is responsible for tomato leaf curl New Delhi virus pathogenicity in tomato.  FRONTIERS IN PLANT SCIENCE.  14, 
  • (2023)  Construction of an Agroinfectious Clone of a Korean Isolate of Sweet Potato Symptomless Virus 1 and Comparison of Its Infectivity According to Agrobacterium tumefaciens Strains in Nicotiana benthamiana.  PLANT PATHOLOGY JOURNAL.  39,  3
  • (2023)  Comparative Transcriptomic Analysis of Genes in the 20-Hydroxyecdysone Biosynthesis in the Fern Microsorum scolopendria towards Challenges with Foliar Application of Chitosan.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24,  3
  • (2023)  Transcriptional Analysis of the Differences between ToLCNDV-India and ToLCNDV-ES Leading to Contrary Symptom Development in Cucumber.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24,  3
  • (2023)  An Effective Integrated Machine Learning Framework for Identifying Severity of Tomato Yellow Leaf Curl Virus and Their Experimental Validation.  RESEARCH.  6, 
  • (2022)  A Novel Approach of Antiviral Drugs Targeting Viral Genomes.  MICROORGANISMS.  10,  8
  • (2022)  Oral administration of Euglena gracilis paramylon ameliorates chemotherapy-induced leukocytopenia and gut dysbiosis in mice.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.  211, 
  • (2022)  A Therapeutically Active Minibody Exhibits an Antiviral Activity in Oseltamivir-Resistant Influenza-Infected Mice via Direct Hydrolysis of Viral RNAs.  VIRUSES-BASEL.  14,  5
  • (2022)  Different Infectivity of Mediterranean and Southern Asian Tomato Leaf Curl New Delhi Virus Isolates in Cucurbit Crops.  PLANTS-BASEL.  11,  5
  • (2022)  Preliminary Study to Investigate the Effect of Lactobacillus Reuteri Administration on Growth Performance, Immunological, Gut Microbiome and Intestinal Mucosa of Chicken.  BRAZILIAN JOURNAL OF POULTRY SCIENCE.  24,  4
  • (2021)  Butein-Enriched Fractions of Butea monosperma (Lam.) Taub. Flower Decrease Weight Gains and Increase Energy Expenditure in High-Fat Diet-Induced Obese Mice.  JOURNAL OF MEDICINAL FOOD.  24,  12
  • (2021)  Identification of a novel geminivirus in fraxinus rhynchophylla in Korea.  VIRUSES-BASEL.  13,  12
  • (2021)  Tomato Yellow Leaf Curl Virus Infection in a Monocotyledonous Weed (Eleusine indica).  PLANT PATHOLOGY JOURNAL.  37,  6
  • (2021)  Plum pox virus: diagnosis and spread inhibition by weed control.  JOURNAL OF PLANT DISEASES AND PROTECTION.  128,  4
  • (2021)  Adaptation and Codon-Usage Preference of Apple and Pear-Infecting Apple Stem Grooving Viruses.  MICROORGANISMS.  9,  6
  • (2021)  Broad-Spectrum Antiviral Activity of 3D8, a Nucleic Acid-Hydrolyzing Single-Chain Variable Fragment (scFv), Targeting SARS-CoV-2 and Multiple Coronaviruses In Vitro.  VIRUSES-BASEL.  13,  4
  • (2021)  Inclusion ofLactobacillus salivariusstrain revealed a positive effect on improving growth performance, fecal microbiota and immunological responses in chicken.  ARCHIVES OF MICROBIOLOGY.  203,  2
  • (2021)  Zooming on dynamics of marine microbial communities in the phycosphere of Akashiwo sanguinea (Dinophyta) blooms.  MOLECULAR ECOLOGY.  30,  1
  • (2021)  De novo transcriptome assembly of two microsorum fern species identifies enzymes required for two upstream pathways of phytoecdysteroids.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22,  4

단행본

  • (1999)  Developmental and structural aspects of root organogenesis (In Morphogenesis in plant tisseu culture).  Kluwer Academic Publishers.  공동

특허/프로그램

  • 국내 고구마 잎마림병 감염 DNA 바이러스 유전자 및 재조합 플라스미드.  10-2009-0035784.  20090424.  대한민국
  • 전사 후 유전자 침묵 현상의 억제 활성을 갖는 국내 고구마 잎말림병 감염 DNA 바이러스.  10-2009-0035785.  20090424.  대한민국
  • 항 베타에스트리올 항혈청을 포함하는 베타에스트리올 검출용 바이오센서 및 베타에스트리올 검출 방법.  10-0737230.  20070703.  대한민국
  • 항 비스테리올 항혈청을 포함하는 비스트리올 검출용 바이오센서 및 비스페놀 검출 방법.  10-0737246.  20070703.  대한민국
  • 항 에스트리올 항혈청을 포함하는 에스트리올 검출용 바이오센서 및 에스트리올 검출 방법.  10-0737186.  20070703.  대한민국
  • 곰팡이내 존재하는 ASGV 검출용 프라이머 세트, 이를 이용한 검출 방법 및 키트.  10-0703600.  20070329.  대한민국
  • 베고모바이러스 검출용 프라이머 세트, 이를 이용한 검출방법 및 키트.  10-0703599.  20070329.  대한민국
  • 잔디생장 촉진물질 및 잔디생장 촉진물질의 검정 유전자.  10-0559080.  20060303.  대한민국
  • 항원 항체 반응을 이용한 삭시톡신 검출용 바이오센서.  0483908.  20050408.  대한민국
  • 녹색형광단백질 유전자를 이용한 삭시톡신 검출용 바이오센서.  0459107.  20041119.  대한민국

수상/공훈

  • Reviewer:
  • Journal of Nutrition, Plant Cell Reports, Plant Pathology Journal, Molecules and Cells,
  • Journal of Virological Methods
  • 대표 국제학회, 학술대회 활동:
  • 20141206/ 대만/ 포스터/ 2014 The 5th International Conference of Clinical Plant Science
  • 20141012/ 네덜란드/ 포스터/ 3rd Antivirals Congress
  • 20141103/ 태국/ 포스터/ The 5th Asian Conference on Plant Pathology 2014
  • 20141021/ 대한민국/ 포스터/ The 26th International Conference of the Korean Society for Molecular and Cellular Biology

학술회의논문

  • (2010)  Agroinoculation of cloned HYVV.  6th International Geminivirus Conference.  멕시코
  • (2010)  Molecular characterization of SPLCV.  6th International Geminivirus Conference.  멕시코
  • (2010)  Phylogenentic analysis of TbLCV.  6th International Geminivirus Conference.  멕시코
  • (2010)  Phylogenetic and recombination.  6th International Geminivirus Conference.  멕시코
  • (2010)  Molecular characetrization of SPLCV Korea isolates.  한국분자세포생물학회.  대한민국
  • (2009)  Nuclease 3D8 scFv enhibits an antibody against....  한국분자세포생물학회 정기학술대회.  대한민국
  • (2009)  Microarray analysis of transgenic tobacco nuclies acid hydrolyzing antibody which confers the resistance against DNA and RNA virus infection.  한국육종학회.  대한민국
  • (2009)  핵산 가수분해 항체를 생산하는 바이러스 저항성 담배의 발생과 오이모자이크 바이러스에 대한 과민성 반응.  2009 농업생물공학 우수성과 발표회.  대한민국
  • (2004)  Differentiatial expression patterns of cyclions under cytokinin and photo in rice seedling.  한국식물생명공학회.  대한민국
  • (2004)  Isolation and characterization of D- type cyclin genes in potato.  한국식물생명공학회.  대한민국
  • (2003)  Geminivirus protection by using ssDBA specific catalytic recombinant antibody on tobacco.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2003)  Immunolocalization of four invertase isozymes from different developing stages of pea.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2003)  Molecular analysis of altered gene expression and protein profiles on BCTV infected Arabidopsis.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2003)  Molecular characterization of apple stem grooving virus and its fungus vector in Korea.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2003)  Purification and characetrization of insoluble invertases from pea.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2003)  Purification and characterization of soluble invertases from pea.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2003)  The role of ATHB12, A homeodomain protein in Arabidopsis during plant development.  7th Inbternational Congress of Plant Molecular Biology.  스페인
  • (2002)  Analysis of expression profiles of stress related genes induced by simulated acid rain in Arabidopsis.  한국식물생명공학회추계학술대회.  대한민국
  • (2002)  Interrelation of transcription factor athb-12 expression pattern and BCTV infection.  한국식물생명공학회추계학술대회.  대한민국
  • (2002)  Isolation and characteriation of carrot thaumatin like protein.  한국식물생명공학회추계학술대회.  대한민국